Haku
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Developing a High-Throughput System for monitoring Zebrafish Behaviour
(Åbo Akademi, 2019)
The aim of this thesis project was to develop a high-throughput (HT) system for recording the behaviour of zebrafish larvae in response to light stimuli. This was achieved by using a compatible camera, Raspberry Pi Camera ...
Polyacrylamide Stiffness-gradient Hydrogels : A 2D Culture System to Study Cell Mechano-responsiveness to Substrate Stiffness
(Åbo Akademi, 2019)
Stiffness of the extracellular matrix (ECM) has emerged as a prominent mechanical cue that influences cell behaviour and tissue homeostasis. Importantly, there is growing evidence suggesting that a prolonged dysregulation ...
Identification of glycosylations affected by androgen-regulated process on the surface of extracellular vesicles derived from PCa cell lines
(Åbo Akademi, 2019)
Introduction: Prostate cancer (PCa) is one of the leading death-causing cancers in males. Lack of sensitivity of the current diagnostic approach created an opportunity for a new diagnostic method. Altered glycosylation is ...
Colonocyte Keratins are upregulated in hypoxia and affects nuclear translocation of HIF-1a
(Åbo Akademi, 2019)
The cytoskeleton is divided into three types: microtubules, microfilaments and intermediate filaments (IFs). IFs are further divided into 6 different types. First two types of IFs are type I and type II keratins. Keratins ...