1182 Biokemia, solu- ja molekyylibiologia
Uusimmat viitteet
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Characterization of HSF1 Interactome during Anisomelic Acid Treatment Using TurboID Proximal Labeling
(2023)The heat shock response involves the expression of molecular chaperones that aid in re-folding or degradation of proteins in physiological and pathological conditions that promote accumulation of misfolded proteins. A key ...Embargo 16.6.2024 asti -
Genetisk analys av Dredd-förmedlad klyvning av Kenny i bananflugans tarm
(2023)Transkriptionsfaktorn nukleär faktor kappa-lättkedjeförstärkare av aktiverade B-celler (eng. nuclear factor kappa-light-chain-enhancer of activated B cells, NF-κB) är mycket viktig för det molekylära immunförsvaret hos ... -
Folate receptor beta as an imaging target in myocardial infarction
(2023)For decades, myocardial infarction (MI) has been one of the leading causes of mortality worldwide. MI is characterized by different stages of inflammation of myocardium up to subsequent fibrosis. During the inflammatory ... -
Evaluating tumour-specificity of mesoporous silica nanoparticle drug delivery in organotypic 3D cultures
(2022)Salassapidettävä 31/10/2026 asti. -
Funktionella och strukturella studier av kollagenbindande α1 och α2 integrin I-domäner
(2022)Integriner är heterodimera proteiner som består av en α-underenhet och en β-underenhet. De medverkar i cell–cell- samt cell-extracellulära matrixinteraktioner och har viktiga roller vid flera olika sjukdomar, såsom cancer, ... -
Towards targeted antibiotics against Lyme disease - Ligand binding properties of Borrelia burgdorferi BmpD
(2022)Salassapidettävä 01/10/2026 asti. -
Zero-Cost Deep Learning to Enhance Microscopy
(2022)Combining microscopy image acquisition and deep learning improves image processing and analytics. However, deep learning requires knowledge of information technology and expensive hardware. Also, proper training of the ... -
dSting reglerar den antivirala NF-ĸB-förmedlade immunresponsen i bananflugan
(2022)Drosophila melanogaster (bananflugan) utgör en utmärkt modellorganism för studier inom immunförsvaret – närmare sagt det ospecifika immunförsvaret, då bananflugan saknar ett specifikt immunförsvar. Bananflugans immunresponser ... -
Identification and Quantitation of Bone Marrow Adipocytes by Immunostaining
(2022)Bone marrow adipocytes (BMAds) have been found to impact other cell populations inside the marrow and they can influence the entire body, but the role of adipocytes in bone physiology has been poorly understood. BMAds can ...Embargo 22.6.2023 asti -
Phenotypic impact of keratin 8/18 downregulation in colonic in vitro 3D cultures
(2022)The second deadliest and third most common type of cancer is colorectal cancer (CRC). The disease mechanism is to a large extent unknown and the number of cases is on the rise in westernized countries. Interestingly, ... -
Ovarian hormones modulating intestinal epithelia – a focus on keratins
(2022)Salassapidettävä 2/6/2024 asti. -
3D structural modeling of Klebsiella pneumoniae SEFIR domain protein and insights into its putative interaction with IL-17 receptor A
(2022)Salassapidettävä 1.6.2026 asti -
The role of IgCAM in cancer cell adhesion and migration
(2022)Cell adhesion and migration are fundamental for the normal development of multicellular organisms. An aberrant cell adhesion and migration is considered a hallmark of the metastatic cascade in cancer progression. Metastasis ...Salassapidettävä 24.3.2027 asti. -
Autoimmunity-associated polymorphisms and their effects on the immunophenotype : Cohort generation and subject immunophenotyping in the Finnish Diabetes Prediction and Prevention study
(2021)Type 1 diabetes (T1D) has a multifactorial etiology wherein both genetic and environmental factors predispose and modulate an individual’s risk of developing the disease. Hereditary factors are perceived to be the fundamental ... -
Molekylära kopplingar mellan signalförmedlare i olika NF-κB-räckor i epitelceller i Drosophilas tarmkanal
(2021)Bananflugan (Drosophila melanogaster) är en utmärkt modellorganism för att studera cell signaleringsräckor som reglerar aktiveringen av NF-κB-transkriptionsfaktorer. I Drosophila har två NF-κB-immunsignaleringsräckor ... -
Karakterisering av Notch1 fosforylering under replikationsstress
(2021)Notch1 har en betydande roll i många av cellens funktioner. Tidigare studier visar att Notch deltar i regleringen av ATM/ATR-aktiveringen vid replikationsstress genom att binda till ATM, vilket inhiberar autofosforyleringen ...Salassapidettävä 6.9.2025 asti. -
Comparison of in vitro high content screening methods for drug genotoxicity
(2021)Detection of chemicals that induce damage to the DNA is an important aspect in drug development. The recognition of these chemicals is based on in vitro studies followed by in vivo studies, the latter being both expensive ... -
Engineering DoxA activity through the manipulation of associated electron transport partners
(2021)Doxorubicin (DXR) is an anthracycline produced by some strains of the bacterium Streptomyces peucetius subsp. caesius. It is one of the most commonly used drugs in the treatment of several different types of cancer. It is ...Embargo 14/6/2022 asti. -
Modulation of Human Papilloma Virus transcription by Jagged1 in cervical cancer cell lines
(2021)The Human Papilloma Virus (HPV) is a common sexually transmitted pathogen and the etiological agent for developing cervical cancer (CC). From the high-risk HPVs (hr-HPV), types 16 and 18 are the most prevalent ones. HPV ...
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