Selaus asiasanan mukaan kokoelmassa 1182 Biokemia, solu- ja molekyylibiologia
Viitteet 1-20 / 26
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Biogeochemistry in acid sulphate soil landscapes and small urban centres in Western Finland
(Åbo Akademi - Åbo Akademi University, 29.01.2010)The overall purpose of this thesis was to increase the knowledge on the biogeochemistry of rural acid sulphate (AS) soil environments and urban forest ecosystems near small towns in Western Finland. In addition, the potential ... -
Bioinformatics Characterization of Amine Oxidases
(Åbo Akademi - Åbo Akademi University, 14.12.2018)Amine oxidases catalyse the oxidative degradation of amines into the corresponding aldehyde, ammonia and hydrogen peroxide. They can be classified into different subfamilies based on the prosthetic group: (1) proteins with ... -
Contributions to risk assessment of microcystins, cyanobacterial toxins : development of immunoanalysis and characterization of microcystin variants
(Åbo Akademi - Åbo Akademi University, 15.06.2012) -
Effects of methylation and hydroxylation of sphingomyelins on their biophysical properties and interactions with cholesterol
(Åbo Akademi - Åbo Akademi University, 28.09.2012) -
Fast LC-MS detection of cyanobacteria peptide hepatotoxins – method development for determination of total contamination levels in biological materials
(Åbo Akademi - Åbo Akademi University, 05.11.2010) -
From protein structure to function with bioinformatics
(Åbo Akademi - Åbo Akademi University, 27.11.2015)It has long been known that amino acids are the building blocks for proteins and govern their folding into specific three-dimensional structures. However, the details of this process are still unknown and represent one of ... -
Glycolipid and ceramide transfer proteins : important determinants for their function
(Åbo Akademi - Åbo Akademi University, 12.04.2013)- -
Identification of Three Conserved Interaction Zones Around the Catalytic Machinery of alpha/beta- Hydrolase Fold Enzymes
(Åbo Akademi - Åbo Akademi University, 06.03.2020)The alpha/beta-Hydrolases (ABH) comprise one of the largest structural families of proteins, found in all organisms. Although they share low sequence similarity, the ABH fold enzymes maintain a common catalytic domain, the ... -
Integrin evolution : from prokaryotes to the diversification within chordates
(Åbo Akademi - Åbo Akademi University, 14.10.2016)Integrins are a family of large multi-domain cell surface receptors responsible for bidirectional signaling in response to cell-cell, cell-extracellular matrix interactions as well as intracellular interactions. Intrgrins ... -
Membrane lipid frustration : Contribution of ceramide and its effects on lateral segregation
(Åbo Akademi University, 17.06.2021)Ceramides are both sphingolipid precursor molecules and breakdown products with effects on membranes that are of interest both from biophysical and physiological points of view. When present in a membrane, ceramide induces ... -
Membrane properties of structurally modified ceramides : effects on lipid lateral distribution and sphingomyelin-interactions in artificial bilayer membranes
(Åbo Akademi - Åbo Akademi University, 14.03.2014)Ceramides comprise a class of sphingolipids that exist only in small amounts in cellular membranes, but which have been associated with important roles in cellular signaling processes. The influences that ceramides have ... -
Molecular Basis of the Sticholysin-Membrane Interaction : On the Structure of the Pore and the Effects of Lipids
(Åbo Akademi University Universidad Complutense de Madrid, 18.06.2021)The usefulness of toxicity across the tree of life is far beyond doubt. Most, if not all, organisms produce compounds that can be used for attack and/or defense against external entities. Some of the most specialized of ... -
Moving lipids : ceramides, glycosphingolipids and the glycolipid transfer protein
(Åbo Akademi - Åbo Akademi University, 20.05.2016)Lipid movement in cells occurs by a variety of methods. Lipids diffuse freely along the lateral plane of a membrane and can translocate between the lipid leaflets, either spontaneously or with the help of enzymes. Lipid ... -
Muscarinic toxins : characterization of adrenoceptor binding and applicability of membrane anchoring via glycosylphosphatidylinositol tail
(Åbo Akademi - Åbo Akademi University, 31.01.2014)Adrenoceptors (ARs), G-protein coupled receptors (GPCRs) at the plasma membrane, respond to endogenous catecholamines noradrenaline and adrenaline. These receptors mediate several important physiological functions being ... -
Phosphorylation as a mediator of protein function in cell migration, differentiation, and death : vimentin, AATF, and Par-4 in the spotlight
(Åbo Akademi - Åbo Akademi University, 11.11.2016)Protein phosphorylation is a major regulator of cellular signaling. It functions when a kinase joins a phosphate group to a protein, or when a phosphatase strips off a phosphate group from serine, threonine, or tyrosine ... -
Prediction of 3D structure and ligand-binding properties : ABC transporters and flavodiiron proteins from Synechocystis sp. strain PCC 6803
(Åbo Akademi - Åbo Akademi University, 24.05.2013)Cyanobacteria are unicellular, non-nitrogen-fixing prokaryotes, which perform photosynthesis similarly as higher plants. The cyanobacterium Synechocystis sp. strain PCC 6803 is used as a model organism in photosynthesis ... -
Regulation of Death Receptor Responses by Hyperthermia
(Åbo Akademi - Åbo Akademi University, 01.06.2007)Cells need a variety of responses to protect themselves against stresses caused by changes in the environment. Likewise, a complex apoptotic machinery is necessary for elimination of cells that are no longer needed in the ... -
Removal of cyanobacterial toxins by strains of probiotic bacteria
(Åbo Akademi - Åbo Akademi University, 21.12.2011) -
Specificity Determining Features at the Interface of Biomolecular Complexes as Regulators of Biological Functions
(Åbo Akademi - Åbo Akademi University, 13.01.2023)Amino acid residues at the biomolecular interface play essential roles in many biological and cellular processes; relevant to this thesis, protein-protein interactions regulate signaling pathways and enzymatic activity, ... -
Structural characterization of avidins with novel binding properties
(Åbo Akademi - Åbo Akademi University, 14.09.2018)Avidin (Avd) is a protein first discovered in chicken egg white, and later in other birds, reptiles, amphibians and lancelet. Apart from these eukaryoticspecies, Avd is also identified in few fungal and in many bacterial ...