Selaus syöttöajan mukaan kokoelmasssa 1182 Biokemia, solu- ja molekyylibiologia

The usefulness of toxicity across the tree of life is far beyond doubt. Most, if not all, organisms produce compounds that can be used for attack and/or defense against external entities. Some of the most specialized of ...

KRAS mutations account globally for about one million deaths per year, but there is as yet no approved drug against KRAS. K-Ras proteins are organized into di-/oligomeric nanoscale signaling complexes, known as nanoclusters ...

The alpha/beta-Hydrolases (ABH) comprise one of the largest structural families of proteins, found in all organisms. Although they share low sequence similarity, the ABH fold enzymes maintain a common catalytic domain, the ...

To be able to target cells of interest is one of the key aims in medicine today, because it could minimize side effects of drugs. This is of special importance in cancer therapies, were the treatment has serious side-effects ...

Avidin (Avd) is a protein first discovered in chicken egg white, and later in other birds, reptiles, amphibians and lancelet. Apart from these eukaryoticspecies, Avd is also identified in few fungal and in many bacterial ...

An industrially and pharmaceutically important filamentous fungus, Aspergillus terreus, is known to biosynthesise plentiful natural products including lovastatin, a serum cholesterol lowering agent. A. terreus has also ...

All cells in a human body are constantly exposed to environmental fluctuations to which the cells must respond. Most of the cellular responses are mediated by proteins that are specifically regulated according to the ...

Ceramide belongs to an important class of sphingolipids and it constitutes the hydrophobic backbone of all complex sphingolipids. Ceramide plays an important role in different biological processes such as cell signaling, ...

Thyroid cancer is the most common endocrine cancer and currently there is no effective treatment available against the most aggressive and highly invasive forms of thyroid cancer. Sphingosine 1-phosphate (S1P) is a bioactive ...