Haku
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Structural characterization of avidins with novel binding properties
(Åbo Akademi - Åbo Akademi University, 2018-09-14)
Avidin (Avd) is a protein first discovered in chicken egg white, and later in other birds, reptiles, amphibians and lancelet. Apart from these eukaryoticspecies, Avd is also identified in few fungal and in many bacterial ...
The regulatory role of butyrolactone I in the filamentous fungus Aspergillus terreus
(Åbo Akademi - Åbo Akademi University, 2018-06-08)
An industrially and pharmaceutically important filamentous fungus, Aspergillus terreus, is known to biosynthesise plentiful natural products including lovastatin, a serum cholesterol lowering agent. A. terreus has also ...
Impact of lipid-lipid interactions on lateral segregation in bilayers
(Åbo Akademi - Åbo Akademi University, 2018-05-18)
The vast diversity of lipid species found in cells suggests that structural variation of lipids is essential for the normal function of the cell. One essential reason could be the formation of lateral heterogeneity in cell ...
The role of keratins in proliferation, differentiation and hypoxia signaling in colonic epithelia
(Åbo Akademi - Åbo Akademi University, 2018-08-17)
Keratin (K) intermediate filament proteins are important in stress protection and in providing mechanical support to colonic epithelial cells. Deletion of K8 in mice (K8-/-) leads to colonic epithelial hyperproliferation, ...
Bioinformatics Characterization of Amine Oxidases
(Åbo Akademi - Åbo Akademi University, 2018-12-14)
Amine oxidases catalyse the oxidative degradation of amines into the corresponding aldehyde, ammonia and hydrogen peroxide. They can be classified into different subfamilies based on the prosthetic group: (1) proteins with ...
Regulation of cellular stress proteins in physiology and disease
(Åbo Akademi - Åbo Akademi University, 2018-05-18)
All cells in a human body are constantly exposed to environmental fluctuations to which the cells must respond. Most of the cellular responses are mediated by proteins that are specifically regulated according to the ...
Keratiner i den endokrina bukspottkörteln : Nya regulatorer av cellulära processer i β-celler
(Åbo Akademi - Åbo Akademi University, 2018-02-09)