Viitteet 41-50 / 53
Role of the canonical transient receptor potential channel 2 (TRPC2) in thyroid cell function
(Åbo Akademi - Åbo Akademi University, 2013-02-08)
Stress management : multilayer regulation of the heat shock response
(Åbo Akademi - Åbo Akademi University, 2017-04-21)
Protein-damaging stresses, such as exposure to elevated temperature, alcohol, and heavy metals and microbial infections, increase the amount of misfolded proteins in cells, which may lead to formation of toxic protein ...
Prediction of 3D structure and ligand-binding properties : ABC transporters and flavodiiron proteins from Synechocystis sp. strain PCC 6803
(Åbo Akademi - Åbo Akademi University, 2013-05-24)
Cyanobacteria are unicellular, non-nitrogen-fixing prokaryotes, which perform photosynthesis similarly as higher plants. The cyanobacterium Synechocystis sp. strain PCC 6803 is used as a model organism in photosynthesis ...
Targeting oncogenic signaling proteins : new insights using a FRET-based chemical biology approach
(Åbo Akademi - Åbo Akademi University, 2016-01-15)
Cancer affects more than 20 million people each year and this rate is increasing globally. The Ras/MAPK-pathway is one of the best-studied cancer signaling pathways. Ras proteins are mutated in almost 20% of all human ...
Biogeochemistry in acid sulphate soil landscapes and small urban centres in Western Finland
(Åbo Akademi - Åbo Akademi University, 2010-01-29)
The overall purpose of this thesis was to increase the knowledge on the biogeochemistry of rural acid sulphate (AS) soil environments and urban forest ecosystems near small towns in Western Finland. In addition, the potential ...
Choosing the target loci : heat shock factors HSF1 and HSF2 as regulators of cell stress and development
(Åbo Akademi - Åbo Akademi University, 2014-08-29)
Heat shock factors (HSFs) are an evolutionarily well conserved family of transcription factors that coordinate stress-induced gene expression and direct versatile physiological processes in eukaryote organisms. The ...
Effects of methylation and hydroxylation of sphingomyelins on their biophysical properties and interactions with cholesterol
(Åbo Akademi - Åbo Akademi University, 2012-09-28)
Glycolipid and ceramide transfer proteins : important determinants for their function
(Åbo Akademi - Åbo Akademi University, 2013-04-12)
Identification of Three Conserved Interaction Zones Around the Catalytic Machinery of alpha/beta- Hydrolase Fold Enzymes
(Åbo Akademi - Åbo Akademi University, 2020-03-06)
The alpha/beta-Hydrolases (ABH) comprise one of the largest structural families of proteins, found in all organisms. Although they share low sequence similarity, the ABH fold enzymes maintain a common catalytic domain, the ...
Regulation of Notch Signaling by Intracellular Trafficking
(Åbo Akademi - Åbo Akademi University, 2020-02-21)
The Notch signaling pathway is one of the essential mediators of cell-cell communication during development of multicellular organisms. Notch signaling is based on receptors and ligands that interact between neighboring ...