Viitteet 21-30 / 53
Studies on membrane properties of cholesterol and 3-beta modified sterol analogs
(Åbo Akademi - Åbo Akademi University, 2014-11-28)
Cholesterol (Chol) is an important lipid in cellular membranes functioning both as a membrane fluidity regulator, permeability regulator and co-factor for some membrane proteins, e.g. G-protein coupled receptors. It also ...
Moving lipids : ceramides, glycosphingolipids and the glycolipid transfer protein
(Åbo Akademi - Åbo Akademi University, 2016-05-20)
Lipid movement in cells occurs by a variety of methods. Lipids diffuse freely along the lateral plane of a membrane and can translocate between the lipid leaflets, either spontaneously or with the help of enzymes. Lipid ...
Contributions to risk assessment of microcystins, cyanobacterial toxins : development of immunoanalysis and characterization of microcystin variants
(Åbo Akademi - Åbo Akademi University, 2012-06-15)
From protein structure to function with bioinformatics
(Åbo Akademi - Åbo Akademi University, 2015-11-27)
It has long been known that amino acids are the building blocks for proteins and govern their folding into specific three-dimensional structures. However, the details of this process are still unknown and represent one of ...
Regulation of HSF2 and its function in mitosis
(Åbo Akademi - Åbo Akademi University, 2014-09-26)
The cell is continuously subjected to various forms of external and intrinsic proteindamaging stresses, including hyperthermia, pathophysiological states, as well as cell differentiation and proliferation. Proteindamaging ...
Lethal weapons : novel approaches for receptor-targeted cancer cell elimination
(Åbo Akademi - Åbo Akademi University, 2010-12-17)
The currently used forms of cancer therapy are associated with drug resistance and toxicity to healthy tissues. Thus, more efficient methods are needed for cancer-specific induction of growth arrest and programmed cell ...
Kinase function in Parkinson’s disease and neuronal transport
(Åbo Akademi - Åbo Akademi University, 2017-11-03)
Nanoclustering augmentation : a novel mechanism of Ras activation in cancer
(Åbo Akademi - Åbo Akademi University, 2016-02-12)
Proteins of the Ras family are central regulators of crucial cellular processes, such as proliferation, differentiation and apoptosis. Their importance is emphasized in cancer, in which the isoforms H-ras, N-ras and K-ras ...
Dynamic interplay between the intermediate filament protein nestin and Cyclin-dependent kinase 5
(Åbo Akademi - Åbo Akademi University, 2010-10-29)
Tuning cell motility : roles of nestin and vimentin in cancer cell invasion and motility
(Åbo Akademi - Åbo Akademi University, 2014-05-16)
The cytoskeleton is a key feature of both prokaryotic and eukaryotic cells. Itis comprised of three protein families, one of which is the intermediate filaments (IFs). Of these, the IFs are the largest and most diverse. ...