Haku
Viitteet 11-20 / 25
The regulatory role of butyrolactone I in the filamentous fungus Aspergillus terreus
(Åbo Akademi - Åbo Akademi University, 2018-06-08)
An industrially and pharmaceutically important filamentous fungus, Aspergillus terreus, is known to biosynthesise plentiful natural products including lovastatin, a serum cholesterol lowering agent. A. terreus has also ...
Bioinformatics Characterization of Amine Oxidases
(Åbo Akademi - Åbo Akademi University, 2018-12-14)
Amine oxidases catalyse the oxidative degradation of amines into the corresponding aldehyde, ammonia and hydrogen peroxide. They can be classified into different subfamilies based on the prosthetic group: (1) proteins with ...
Muscarinic toxins : characterization of adrenoceptor binding and applicability of membrane anchoring via glycosylphosphatidylinositol tail
(Åbo Akademi - Åbo Akademi University, 2014-01-31)
Adrenoceptors (ARs), G-protein coupled receptors (GPCRs) at the plasma membrane, respond to endogenous catecholamines noradrenaline and adrenaline. These receptors mediate several important physiological functions being ...
Studies on membrane properties of cholesterol and 3-beta modified sterol analogs
(Åbo Akademi - Åbo Akademi University, 2014-11-28)
Cholesterol (Chol) is an important lipid in cellular membranes functioning both as a membrane fluidity regulator, permeability regulator and co-factor for some membrane proteins, e.g. G-protein coupled receptors. It also ...
Removal of cyanobacterial toxins by strains of probiotic bacteria
(Åbo Akademi - Åbo Akademi University, 2011-12-21)
Contributions to risk assessment of microcystins, cyanobacterial toxins : development of immunoanalysis and characterization of microcystin variants
(Åbo Akademi - Åbo Akademi University, 2012-06-15)
Fast LC-MS detection of cyanobacteria peptide hepatotoxins – method development for determination of total contamination levels in biological materials
(Åbo Akademi - Åbo Akademi University, 2010-11-05)
From protein structure to function with bioinformatics
(Åbo Akademi - Åbo Akademi University, 2015-11-27)
It has long been known that amino acids are the building blocks for proteins and govern their folding into specific three-dimensional structures. However, the details of this process are still unknown and represent one of ...
VAP-1 as drug target in inflammation : structural features determining ligand interactions
(Åbo Akademi - Åbo Akademi University, 2015-12-05)
Vascular adhesion protein-1 (VAP-1), which belongs to the copper amine oxidases (CAOs), is a validated drug target in inflammatory diseases. Inhibition of VAP-1 blocks the leukocyte trafficking to sites of inflammation and ...
Moving lipids : ceramides, glycosphingolipids and the glycolipid transfer protein
(Åbo Akademi - Åbo Akademi University, 2016-05-20)
Lipid movement in cells occurs by a variety of methods. Lipids diffuse freely along the lateral plane of a membrane and can translocate between the lipid leaflets, either spontaneously or with the help of enzymes. Lipid ...