Haku
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Phosphorylation as a mediator of protein function in cell migration, differentiation, and death : vimentin, AATF, and Par-4 in the spotlight
(Åbo Akademi - Åbo Akademi University, 2016-11-11)
Protein phosphorylation is a major regulator of cellular signaling. It functions when a kinase joins a phosphate group to a protein, or when a phosphatase strips off a phosphate group from serine, threonine, or tyrosine ...
Moving lipids : ceramides, glycosphingolipids and the glycolipid transfer protein
(Åbo Akademi - Åbo Akademi University, 2016-05-20)
Lipid movement in cells occurs by a variety of methods. Lipids diffuse freely along the lateral plane of a membrane and can translocate between the lipid leaflets, either spontaneously or with the help of enzymes. Lipid ...
Integrin evolution : from prokaryotes to the diversification within chordates
(Åbo Akademi - Åbo Akademi University, 2016-10-14)
Integrins are a family of large multi-domain cell surface receptors responsible for bidirectional signaling in response to cell-cell, cell-extracellular matrix interactions as well as intracellular interactions. Intrgrins ...