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Cellular regulation of the Notch signaling pathway by Notch-interacting proteins
(Åbo Akademi University, 25.09.2020)The Notch signaling mechanism is a crucial regulator of stem cells during development and tissue regeneration. Transcriptional activation of Notch target genes requires cleavage of the Notch receptor in response to ligand ... -
Cellular responses to stress and kinase signaling activation : apoptosis and differentiation
(Åbo Akademi - Åbo Akademi University, 13.08.2013)Stress signals are often sensed by membrane-bound proteins which translate signals into the chemical modification of molecules, most notably protein kinases. These kinases, in turn, transmit the decoded message through a ... -
Characterisation of waste for combustion : with special reference to the role of zinc
Report / Åbo Akademi, Process Chemistry Centre : 13-04 (Åbo Akademi University, Process Chemistry Centre, 11.12.2013)Waste combustion has gone from being a volume reducing discarding-method to an energy recovery process for unwanted material that cannot be reused or recycled. Different fractions of waste are used as fuel today, such as; ... -
Charge collection in thin-film devices based on low-mobility semiconductors : Theory, simulation, and applications to organic solar cells
(Åbo Akademi - Åbo Akademi University, 18.06.2018) -
Charge transport in disordered materials : simulations, theory, and numerical modeling of hopping transport and electron-hole recombination
(Åbo Akademi - Åbo Akademi University, 19.08.2011)Min avhandling behandlar hur oordnade material leder elektrisk ström. Bland materialen som studeras finns ledande polymerer, d.v.s. plaster som leder ström, och mer allmänt organiska halvledare. Av de här materialen har ... -
Chemical changes in biomass during torrefaction
Åbo Akademi, Faculty of Science and Engineering, Johan Gadolin Process Chemistry Centre : 16-01 (Åbo Akademi University, Johan Gadolin Process Chemistry Centre, 22.01.2016)Torrefaction is moderate thermal treatment (~200-300 °C) of biomass in an inert atmosphere. The torrefied fuel offers advantages to traditional biomass, such as higher heating value, reduced hydrophilic nature, increased ... -
Chemical engineering of surface coatings for natural stones
(Åbo Akademi - Åbo Akademi University, 24.02.2017)Natural stones are materials widely used in today’s architecture. White stones (such as marble) and speckled stones (such as granite) are regarded as suitable for decorative purposes and as construction materials. A major ... -
Choosing the target loci : heat shock factors HSF1 and HSF2 as regulators of cell stress and development
(Åbo Akademi - Åbo Akademi University, 29.08.2014)Heat shock factors (HSFs) are an evolutionarily well conserved family of transcription factors that coordinate stress-induced gene expression and direct versatile physiological processes in eukaryote organisms. The ... -
Climate driven changes in temperature, pH and food quality : effects on copepod reproduction
(Åbo Akademi - Åbo Akademi University, 12.10.2012)Increased emissions of greenhouse gases into the atmosphere are causing an anthropogenic climate change. The resulting global warming challenges the ability of organisms to adapt to the new temperature conditions. However, ... -
Coastal Habitats and their Importance for the Biodiversity of Faunal Communities
(Åbo Akademi - Åbo Akademi University, 24.06.2020)Coastal habitats represent highly productive areas serving important functions for multiple organism groups. These shallow areas generally maintain high faunal biodiversity, providing important ecosystem goods and services, ... -
Combining model-based testing and stepwise formal development
TUCS Dissertations : 130 (Turku Centre for Computer Science (TUCS), 04.10.2010) -
Combustion properties of biomass residues rich in phosphorus
Report / Åbo Akademi, Process Chemistry Centre : 12-02 (Åbo Akademi University, Process Chemistry Centre, 04.04.2012)The currently-used sources of biomass are limited so new ones are required in order to meet the European Union target and to satisfy the constantly-increasing demand for energy. This is why energy recovery from residues ... -
Computational chemistry studies of wood-derived lignans
(Åbo Akademi - Åbo Akademi University, 31.05.2013)This thesis is based on computational chemistry studies on lignans, focusing on the naturally occurring lignan hydroxymatairesinol (HMR) (Papers I II) and on TADDOL-like conidendrin-based chiral 1,4-diol ligands (LIGNOLs) ... -
Computational models for and from biology : simple gene assembly and reaction systems
TUCS Dissertations : 205 (Turku Centre for Computer Science (TUCS), 06.11.2015)The advancement of science and technology makes it clear that no single perspective is any longer sufficient to describe the true nature of any phenomenon. That is why the interdisciplinary research is gaining more attention ... -
Computational Network Analytics for Applications in Biomedicine
(Åbo Akademi - Åbo Akademi University, 03.06.2022)Network medicine has recently emerged as a field of research focusing on the analysis of networks modelling complex biological systems, for a better understanding of diseases and corresponding treatment. Building on results ... -
Consistency of UML based designs using ontology reasoners
TUCS Dissertations : 168 (Turku Centre for Computer Science (TUCS), 19.12.2013)Software plays an important role in our society and economy. Software development is an intricate process, and it comprises many different tasks: gathering requirements, designing new solutions that fulfill these requirements, ... -
Context-specific independence in graphical models
(Åbo Akademi - Åbo Akademi University, 21.11.2014)The theme of this thesis is context-speci c independence in graphical models. Considering a system of stochastic variables it is often the case that the variables are dependent of each other. This can, for instance, be ... -
Contributions to risk assessment of microcystins, cyanobacterial toxins : development of immunoanalysis and characterization of microcystin variants
(Åbo Akademi - Åbo Akademi University, 15.06.2012) -
Copepods in a changing sea : ocean acidification, long-term changes and short-term variability
(Åbo Akademi - Åbo Akademi University, 19.05.2017)The rapid increase in atmospheric carbon dioxide is causing global warming but also changes in the ocean chemistry. When carbon dioxide dissolves in seawater it changes the carbonate chemistry towards lower levels of ... -
Corrosion behaviour of boiler tube materials during combustion of fuels containing Zn and Pb
Report / Åbo Akademi, Process Chemistry Centre : 12-03 (Åbo Akademi University, Process Chemistry Centre, 16.06.2012)Many power plants burning challenging fuels such as waste-derived fuels experience failures of the superheaters and/or increased waterwall corrosion due to aggressive fuel components already at low temperatures. To ...